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Botox vs. Xeomin: What’s the Difference & Who’s a Good Fit?

Smooth, natural results start with the right choice. Here’s how to know which wrinkle treatment is right for you.

If you’re starting to notice frown lines, crow’s feet, or forehead wrinkles, you may have already searched “anti-aging injectables" to figure out which option is best. At Bianca Esthetics, we meet clients every week from McKinney, Frisco, and surrounding North Texas areas who want smoother, more youthful-looking skin, but feel unsure which injectable to trust.

This guide will help you understand the real differences between Botox and Xeomin, so you can choose with confidence and feel amazing in your skin.

What Are Botox and Xeomin? (The Basics)

Both Botox and Xeomin are FDA‑approved neuromodulators made from botulinum toxin type A, a purified ingredient that gently relaxes facial muscles responsible for expression lines. These tiny, natural muscle movements (like frowning, smiling, or squinting) create dynamic wrinkles over time. By calming this muscle activity, Botox and Xeomin help smooth the skin and prevent those lines from becoming deeper and more permanent.

They’re most commonly used to treat:

Beyond softening wrinkles, these treatments also have a preventative anti‑aging benefit. Starting early can help train your facial muscles to relax, slowing down wrinkle formation before lines become etched into the skin. Many clients in their late 20s to 40s use neuromodulators not only to correct existing wrinkles but also to maintain smoother, more youthful skin over time.

At Bianca Esthetics, every injectable treatment is customized to your unique facial anatomy and goals. Whether you’re looking for a subtle refresh, visible rejuvenation, or long‑term wrinkle prevention, your provider will help you choose the right product, dose, and technique for natural, balanced results.

While Botox and Xeomin perform similarly, there are a few key differences in their formulation and how they interact with your body, which we’ll explore next.

Key Differences: Botox vs. Xeomin

Formula

Botox includes protective proteins surrounding the active ingredient, while Xeomin is a “naked” neurotoxin, meaning it contains only the active ingredient with no accessory proteins. This purity may reduce the risk of developing resistance over time.

Onset Time

Botox typically begins working within 3 to 5 days. Xeomin may have a slightly faster onset, with some clients seeing results in as little as 2 to 4 days.

Longevity

Both Botox and Xeomin generally last around 3 to 4 months, depending on factors like your metabolism, treatment area, and consistency of use.

Storage

Botox requires refrigeration, making it slightly more sensitive to handling. Xeomin is more stable at room temperature, which can be beneficial for certain medical practices and clinics.

Suitability for Sensitive Clients

Because Xeomin lacks the additional proteins found in Botox, it’s often preferred by clients with protein sensitivities or those who’ve developed tolerance to other injectables. That said, both options are safe and well-tolerated when administered by a trained provider.

Who Is a Good Fit for Each Option?

Botox may be best if:

Xeomin may be better if:

Some clients also find Xeomin gives a slightly softer, more natural look, though results vary by skin type and treatment area.

Why We Offer Both at Bianca Esthetics

At Bianca Esthetics, we don’t believe in a one-size-fits-all approach. Both Botox and Xeomin are excellent products with slightly different benefits. Our licensed provider will help you decide what’s right for you based on:

What to Expect From Your Injectable Visit

Your visit starts with a personalized consultation. We’ll assess your facial structure, movement patterns, and skin history to create a plan that aligns with your goals.

Treatment itself is quick and minimally invasive:

Results typically start appearing within a few days, with full effect visible in 7–10 days.

Ready to Smooth Wrinkles Your Way?

We proudly serve clients in McKinney, Frisco, Allen, and surrounding North Texas communities from our private skincare studio. Whether you’re exploring injectables for the first time or want a fresh alternative, we’re here to help you look refreshed, not frozen.

Book your quick injectable consult today

Let’s find your perfect fit, together.

Frequently Asked Questions: Botox vs. Xeomin

Is one more affordable than the other?

Generally, Botox and Xeomin are priced similarly per unit, but the total cost can vary based on your facial anatomy, treatment area, and dose. In some cases, Xeomin may be slightly more cost-effective because it doesn’t contain extra proteins, which could mean fewer units are needed for some clients. During your consultation, we’ll give you a clear, personalized quote based on your goals, not just units.

Can I switch between Botox and Xeomin over time?

Absolutely. Many clients start with one product and later switch to the other based on results, availability, or how their body responds. If you’ve developed resistance to Botox over time (which can happen in rare cases), Xeomin’s “naked” formula may be a better fit. We’ll monitor your results and recommend adjustments if needed.

Do the results look or feel different?

Both Botox and Xeomin offer comparable wrinkle-smoothing results when used by a skilled provider. That said, some clients say Xeomin settles a bit faster or feels more “natural,” while others prefer the firming effect they get with Botox. Your facial goals, muscle movement, and past experience will guide which product is best for you.

How long do results last?

On average, both Botox and Xeomin last 3 to 4 months. Some clients find Xeomin lasts a bit longer with consistent use, while others feel Botox maintains results better for their skin. Your provider will help you track longevity and fine-tune your treatment plan as you go.

Is Xeomin really more ‘pure’ than Botox? What does that mean?

Yes, Xeomin contains only botulinum toxin A, with no accessory proteins. This “naked” formula means your body may be less likely to develop antibodies that make the product less effective over time. For first-time users, it’s a great option to consider; for long-time Botox users, it’s a strong alternative if your results plateau.

November 11, 2025